Skip to content
EASY RETURNS | 30 Day Hassle-Free Returns!
EASY RETURNS | 30 Day Hassle-Free Returns!

Excedrin Migraine Pain Relief Caplets, Acetaminophen, Aspirin and Caffeine 300 count

in stock, ready to be shipped
Original price $28.98 - Original price $28.98
Original price
$28.98 - $28.98
Current price $28.98

Experience Fast Relief From Your Toughest Migraines

If you are looking for fast pain relief from your toughest migraine pain and symptoms, all without a prescription, you should consider trying Excedrin Migraine Coated Caplets.

Excedrin Migraine pain reliever caplets are designed specifically to help treat migraine headaches. These pain relief tablets are FDA-approved to treat symptoms including pain, photophobia, nausea, phonophobia and related conditions.

Excedrin Migraine Coated caplets are the first over-the-counter migraine pain reliever to contain three ingredients proven effective at treating disabling migraine pain. In clinical studies, individuals who took Excedrin Migraine caplets while experiencing moderate to severe migraines had effective relief after taking just one dose.

Aspirin Tames Pain-Causing Inflammation

A well-known non-steroidal anti-inflammatory that has been used for more than a century; aspirin works is by blocking the body’s production of prostaglandins in the peripheral nervous system. Aspirin helps to prevent the transmission of pain signals to the brain by stopping the production of prostaglandins.

Acetaminophen: The Tried-and-True Pain Reliever

Acetaminophen, like aspirin, also appears to inhibit enzymes in the body that produce pain-causing prostaglandins. However, while aspirin inhibits prostaglandins in the peripheral nervous system, acetaminophen appears to focus its pain-fighting power in the central nervous system. This allows you to tolerate more pain, therefore providing pain relief.

Caffeine: The Amplifier

Caffeine has been shown to increase the potency of aspirin and acetaminophen—the two pain relievers in Excedrin Migraine — by up to 40 percent. This means less acetaminophen and aspirin is needed to relieve your migraine pain when combined with caffeine.

  • 300 count
  • For ages 18 years and older
  • Take 2 doses per day
  • For some, relieves pain in just 30 minutes 
  • Contains acetaminophen, aspirin and therapeutically active caffeine
  • FDA-approved to treat migraines, including pain, nausea, photophobia and phonophobia, and extreme sensitivity to light and sound
  • Use as directed

Customer Reviews

Based on 143 reviews
Just what I expected
5.0 out of 5 stars Good Product

Good product, that meet the expectations.

5.0 out of 5 stars Ok


5.0 out of 5 stars Is the Best

It's a great product. I really recommend it.

5.0 out of 5 stars Great for our office!

Who doesn't need to keep these in our office?! We keep these stocked.

Amy L Monahan
5.0 out of 5 stars Good med

Work good on me

Bundle & Save

5, 5, 10,
default, percentage, percentage,
1, 2, 3,
{ "Default Title":{"price":"2898","compare_at_price":"","id":"47771600879903","quantity":"34","inv_p":"deny","inv_m":"shopify"} }
{ "Default Title":{"price":"2898","compare_at_price":"","id":"47771600879903","quantity":"34","title":"Default Title","inventory_policy":"deny","inventory_management":"shopify"} }